Synthesis and properties of Poly(vinyl alcohol) hydrogels with high strength and toughness

Chen, Ying; Li, Jie; Lu, Jiawei; Ding, Mengxian

doi:10.1016/j.polymertesting.2022.107516

Cited by 101 publications

(72 citation statements)

References 22 publications

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“…Although the hydrogel adhesion inherently relies on engineering the contact surface at soft and hydrated interfaces, we found the adhesion is also affected by the crosslinking degree of hydrogels. Usually, hydrogels can be prepared by different crosslinking methods, mainly including the freezing–thawing cycle, photo-crosslinking and thermal-crosslinking [ 17 , 18 ]. To prove the generality of this finding, polyvinyl alcohol (PVA), polyacrylamide (PAM) and polyvinyl alcohol-bearing styrylpyridinium group (PVA-SbQ) hydrogels, prepared by the freezing–thawing (F-T) cycle, thermal-crosslinking and photo-crosslinking, respectively, were chosen to study the effect of crosslinking on hydrogel adhesion produced by hydrogen bonding in this study.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

Kumar

et al. 2022

Gels

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The development of adhesive hydrogel materials has brought numerous advances to biomedical engineering. Hydrogel adhesion has drawn much attention in research and applications. In this paper, the study of hydrogel adhesion is no longer limited to the surface of hydrogels. Here, the effect of the internal crosslinking degree of hydrogels prepared by different methods on hydrogel adhesion was explored to find the generality. The results show that with the increase in crosslinking degree, the hydrogel adhesion decreased significantly due to the limitation of segment mobility. Moreover, two simple strategies to improve hydrogel adhesion generated by hydrogen bonding were proposed. One was to keep the functional groups used for hydrogel adhesion and the other was to enhance the flexibility of polymer chains that make up hydrogels. We hope this study can provide another approach for improving the hydrogel adhesion generated by hydrogen bonding.

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Section: Introductionmentioning

confidence: 99%

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

Kumar

et al. 2022

Gels

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“…Hydrogels are a three-dimensional crosslinked polymeric matrix which can maintain its structure while preserving large amounts of water [9,10]. With the capability to mimic the properties of extracellular matrices, cells, and soft tissues, hydrogels are widely used as biomedical implants and tissue substitutes [11,12].…”

Section: Introductionmentioning

confidence: 99%

Injectable PTHF-based thermogelling polyurethane implants for long-term intraocular application

et al. 2022

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Background Hydrogels show great potential to be used for intraocular applications due to their high-water content and similarity to the native vitreous. Injectable thermosensitive hydrogels through a small-bore needle can be used as a delivery system for drugs or a tamponading substitute to treat posterior eye diseases with clear clinical potential. However, none of the currently available thermosensitive hydrogels can provide intraocular support for up to 3 months or more. Method In this study, an injectable polytetrahydrofuran (PTHF)-based thermosensitive hydrogel was synthesized by polyurethane reaction. We examined the injectability, rheological properties, microstructure, cytotoxicity, and in vivo compatibility and stability of the hydrogels in rabbit eyes. Results We found that the PTHF block type and PTHF component ratio could modulate thermogelation properties of the polyurethane polymers. The PTHF-based hydrogel implants retained normal retinal structure and function. Incorporating bioinert PTHF generated highly biocompatible and more stable thermogels in the vitreous cavity, with gel networks and the presence of polymer still observed after 3 months when other thermogels would have been completely cleared. Moreover, despite lacking hydrolytically cleavable linkages, the polymers could be most naturally removed from the native vitreous by bio-erosion without additional surgical interventions. Conclusion Our findings suggest the potential of incorporating hydrophobic bioinert blocks to enhance the in vivo stability of supramolecularly associated hydrogels for long-term intraocular applications. Graphical Abstract

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“…Polymer materials are widely used in petrochemistry, environmental protection, medicine and biology, and other fields because of their high-temperature resistance, high strength, strong toughness, and other advantages. Therefore, polymers are synthesized as filter loss reduction agents in deep well drilling operations [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. Li et al [ 26 ] synthesized a polymer, SPL, by chemically cross-linking starch, polyphenols, and lignosulfonate in a filtration volume of 7.0 mL at 150 °C in water-based drilling fluid.…”

Section: Introductionmentioning

confidence: 99%

New Zwitterionic Polymer as a Highly Effective Salt- and Calcium-Resistant Fluid Loss Reducer in Water-Based Drilling Fluids

Liu

Sun

Ren

et al. 2022

Gels

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To control the filtration loss of drilling fluids in salt–gypsum formations, a novel type of zwitterionic polymer gel (DNDAP) was synthesized by free radical polymerization, which was used as a salt- and calcium-resistant fluid loss reducer for water-based drilling fluids (WBDF). DNDAP was prepared with N, N-dimethylacrylamide (DMAA), N-vinylpyrrolidone (NVP), Diallyl dimethyl ammonium chloride (DMDAAC), 2-acrylamide-2-methylpropaneonic acid (AMPS), and isopentenol polyether (TPEG) as raw materials. Fourier transform infrared spectroscopy (FT-IR) and proton nuclear magnetic resonance (1H-NMR) were used to characterize the composition and structure of the DNDAP copolymer. The thermal stability of DNDAP was evaluated by the use of thermogravimetric analysis (TGA). WBDF with DNDAP was analyzed for zeta potential and particle size and the corresponding filter cake underwent energy dispersive spectrum (EDS) analysis and scanning electron microscope (SEM) analysis. The results showed that the thermal decomposition of DNDAP mainly occurred above 303 °C. DNDAP exhibits excellent rheological and filtration properties in water-based drilling fluids, even under high-temperature aging (up to 200 °C) and high salinity (20 wt% NaCl or 5 wt% CaCl2) environments. The strong adsorption effect of DNDAP makes the particle size of bentonite reasonably distributed to form a dense mud cake that reduces filtration losses.

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Synthesis and properties of Poly(vinyl alcohol) hydrogels with high strength and toughness

Cited by 101 publications

References 22 publications

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

Injectable PTHF-based thermogelling polyurethane implants for long-term intraocular application

New Zwitterionic Polymer as a Highly Effective Salt- and Calcium-Resistant Fluid Loss Reducer in Water-Based Drilling Fluids

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