Synthesis and properties of pentane amino derivatives

Talybov, A. G.; Mamedbeili, E. G.; Abbasov, V. М.; Кочетков, К. А.

doi:10.1134/s1070363210120091

Russ J Gen Chem

2010

DOI: 10.1134/s1070363210120091

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Synthesis and properties of pentane amino derivatives

A. G. Talybov

E. G. Mamedbeili

V. М. Abbasov

et al.

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Cited by 2 publications

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“…The following supporting information can be downloaded at: , 1 H NMR data and spectrum, HMRS data, character for compound 7a – 7u ; 13 C NMR data and spectrum for compound 7u ; structures of the amide substrates. References [ 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ] are cited in the Supplementary Materials.…”

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One-Pot Route from Halogenated Amides to Piperidines and Pyrrolidines

et al. 2022

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Piperidine and pyrrolidine derivatives are important nitrogen heterocyclic structures with a wide range of biological activities. However, reported methods for their construction often face problems of requiring the use of expensive metal catalysts, highly toxic reaction reagents or hazardous reaction conditions. Herein, an efficient route from halogenated amides to piperidines and pyrrolidines was disclosed. In this method, amide activation, reduction of nitrile ions, and intramolecular nucleophilic substitution were integrated in a one-pot reaction. The reaction conditions were mild and no metal catalysts were used. The synthesis of a variety of N-substituted and some C-substituted piperidines and pyrrolidines became convenient, and good yields were obtained.

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One-Pot Route from Halogenated Amides to Piperidines and Pyrrolidines

et al. 2022

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Synthesis and properties of aminomethoxy derivatives of 1-(butylsulfanyl)pentane

et al. 2017

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Synthesis and properties of pentane amino derivatives

Cited by 2 publications

References 6 publications

One-Pot Route from Halogenated Amides to Piperidines and Pyrrolidines

One-Pot Route from Halogenated Amides to Piperidines and Pyrrolidines

Synthesis and properties of aminomethoxy derivatives of 1-(butylsulfanyl)pentane

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