Synthesis and properties of anhydride of benzo[k,l]selenoxanthene-3,4-dicarboxylic acid

Guttsait, A. V.; Balodis, K. A.; Meirovits, I. A.

doi:10.1007/bf00538073

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2009

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“…The target fluorophores were synthesized from naphthalic acid and purified according to methods reported previously [19,20]. Figure 1 shows the chemical structure of these probes.…”

Section: Chemicalsmentioning

confidence: 99%

3-Isopropyloxy-6-morpholino-2-phenylphenalen-1-one as Lipophilic Fluorescent Probe for Lymphocyte Investigations

Kirilova

Kalnina

2009

Appl Biochem Biotechnol

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Fluorescent properties of two naphthalimides and a phenalenone derivative in organic solvents and when they bind to human peripheral blood lymphocytes were investigated. Different spectral characteristics were observed using lymphocytes of healthy donors and patients with nonmalignant (chronic myeloid leukemia) and malignant (B-cell lymphoid leukemia) diseases. It was found that spectral properties of the used fluorophores in cell suspension qualitatively characterize its structural and functional alterations during pathological phenomena. The intensity of fluorescence increased in samples from patients with B-cell lymphoid leukemia, and the fluorescence maximum shifted to the long-wavelength region by 20 nm compared with normal lymphocytes. It is concluded that 3-isopropyloxy-6-morpholino-2-phenylphenalen-1-one as most promising probe may be applied to the study of malignant diseases.

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“…The target fluorophores were synthesized from naphthalic acid and purified according to methods reported previously [19,20]. Figure 1 shows the chemical structure of these probes.…”

Section: Chemicalsmentioning

confidence: 99%

3-Isopropyloxy-6-morpholino-2-phenylphenalen-1-one as Lipophilic Fluorescent Probe for Lymphocyte Investigations

Kirilova

Kalnina

2009

Appl Biochem Biotechnol

View full text Add to dashboard Cite

show abstract

Synthesis and properties of anhydride of benzo[k,l]selenoxanthene-3,4-dicarboxylic acid

Cited by 1 publication

References 6 publications

3-Isopropyloxy-6-morpholino-2-phenylphenalen-1-one as Lipophilic Fluorescent Probe for Lymphocyte Investigations

3-Isopropyloxy-6-morpholino-2-phenylphenalen-1-one as Lipophilic Fluorescent Probe for Lymphocyte Investigations

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