Synthesis and Preliminary Biological study of New Chalcone Derivatives Containing Isoxazoline Moiety
Huda Ismail Al-Rubaye,
Zahra Mohammed Abbas,
Nahida A. Jinzeel
et al.
Abstract:In this research work, synthesis, antimicrobial and antioxidant bioactivity of a chain of compounds having unsaturated ketones bond and isoxazoline moiety have been described. New chalcone derivatives containing isoxazoline moiety have been synthesized. Generally, Chalcones are unsaturated ketones bearing (-CO-CH=CH-) as reactive ketoethylenic group that give the bright yellow colored compounds due to this chromophore group. Firstly, chalcones (IIa-d) have been prepared by cyclocondensation (Claisen-Schmidt c… Show more
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