Synthesis and predicted antiviral activity of 4-substituted 9,10-anthraquinone derivatives

Abstract

Antiviral activity was predicted by using data from program PASS Online for synthesized compounds against picornavirus, the influenza and the rhinovirus, what fits in today's strategy of creating of the anthraquinone-based anticancer drugs and with antibacterial effect. There are several current methods to synthesize 9,10-anthraquinone, which contain the biogenic amines in the 4-position. Antiviral activity was predicted by using program AVCpred in a percentage of inhibition against deadly viruses like Human immunodeficiency virus (HIV), Hepatitis C virus (HCV), Hepatitis B virus (HBV), Human herpesvirus (HHV)