Synthesis and oxidation of quaternary salts of 1-aminoimidazoles

An efficient and practical synthesis of chiral imidazolium ionic liquids and their application in an enantioselective Michael reaction

“…N-Methylimidazole was employed as a starting material to react with 1-chloro-2,4-dinitrobenzene (Scheme 1), and the desired 1-(2,4-dinitrophenyl)-3-methylimidazolium chloride 1 could be obtained in 22% yield, which is similar to the yield (23%) in the literature 13 and too low for practical use. By changing the reaction conditions, we found that an excellent yield (96%) of 1-(2,4-dinitrophenyl)-3-methylimidazolium chloride 1 could be achieved.…”

“…Synthesis of chiral imidazolium ionic liquids 2-4 Isolated yields. b All products were confirmed by 1 H NMR,13 C NMR, IR and EA. c c = 2g per 100 ml, MeOH.…”

Synthesis, characterisation and insulin-mimetic activity of oxovanadium(IV) complexes with amidrazone derivatives

“…The ligands were prepared according to established procedures [31,33]. The method of preparation is displayed in Scheme 2.…”

A Mild and Convenient Synthetic Method for Arylhydrazones of Methyl Benzoate

“…The former method has been extensively investigated. [2,3] Alternatively, the loss of ammonia and its replacement by a nucleophile may also occur (Sch. [1] The latter method, however, has not been extensively investigated.…”