Synthesis and mesomorphic characterization of novel liquid crystals derived from bioactive natural sterols

Synthesis and mesomorphic characterization of novel amphotropic steroidal esters

“…Our previous studies explored the effect of the steroidal moiety (cholesterol, stigmasterol, and ergosterol) on the mesogenicity of various alkoxy benzoate derivatives of sterols. 42,43 In this report, we elucidate the importance of the nature of the periphery in the steroidal system in their liquid crystalline organization. We have attempted to study the self-organization of ethyleneoxy appended cholesterol and stigmasterol benzoates through POM, DSC, SAXS, and cryo-SEM.…”

Steglich esterification: A versatile synthetic approach toward the synthesis of natural products, their analogues/derivatives

“…The liquid crystals exhibit a number of applications in different fields [ 92 ]. Bhat et al proposed the synthesis of target compounds by employing Steglich esterification as a key step in 2020 [ 93 ]. The first step involved coupling of Stigmasterol 256 with 4-bromo benzoic acid 257 via Steglich esterification in the presence of DCC, DMAP and dichloromethane to obtain sterol 4-bromo benzoates 258 .…”