“…1,2,4-Triazole rings are typically planar aromatic systems, featuring an extensive chemistry [ 10 , 11 ]. 1,2,4-Triazole derivatives represent one of the most biologically active classes of heterocyclic compounds, and their derivatives are characterized with a broad spectrum of biological activity, including anti-cancer activity [ 12 ], antiparasitic activity [ 13 ], larvicidal activity[ 14 ], antifungal activity [ 15 ], herbicidal activity [ 16 , 17 ], antioxidant activity [ 18 ], cytostatic activity [ 19 ], brassinosteroid biosynthesis inhibitors [ 20 ], antimicrobial activity [ 21 ], and so on. Some compounds had been developed as commercial fungicides or herbicides ( Figure 1 ), such as Triadimefon, Triadimenol, Flusilazole, Flupoxamand, and so on.…”