Synthesis and Evaluation of Thermodynamic Solubility of Triazolo Quinolone Class Derivatives in Various Solvents at 298.15-328.15 K

Abstract

The solubility of triazolo quinolone class derivatives in methanol, ethanol, n-propanol, n-butanol and ethyl acetate was measured using a gravimetrical method at temperature ranging from 298.15 K to 328.15 K. The results of these measurements were correlated with semi empirical equations. Some thermodynamic parameters such as dissolution enthalpy, Gibb’s free energy and entropy of mixing have also been calculated.