Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed <i>via</i> expeditious synthesis from isoquinolin-5-ol

Lee, Szu; Chao, Min-Wu; Wu, Yi-Wen; Hsu, Chia-Min; Lin, Tony Eight; Hsu, Kai-Cheng; Pan, Shiow-Lin; Lee, Hsueh-Yun

doi:10.1039/d3ra06600b

RSC Adv.

2023

DOI: 10.1039/d3ra06600b

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Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol

Szu Lee,

Min-Wu Chao,

Yi-Wen Wu

et al.

Abstract: The K2S2O8-mediated generation of p-iminoquinone contributed to the regioselective substitution of isoquinolin-5,8-dione.

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Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol

Abstract: The K2S2O8-mediated generation of p-iminoquinone contributed to the regioselective substitution of isoquinolin-5,8-dione.

Cited by 0 publications

References 35 publications

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