“…The resulting boranated acylmetronidazole was, however, unstable at pH 6.0. A more stable thioether linkage was prepared (Scheme ) via the reaction of 1,2-dibromoethane with 2-methyl-5-NO 2 Im ( 319) to yield 1-(2-bromoehtyl)-2-methyl-5-NO 2 Im ( 378 ), which upon Cs salt coupling with BSH gave the desired 1-[2[(undecahydro- closo -dodecaborato)thio]ethyl)-2-methyl-5-NO 2 Im ( 379 ) 58
…”