Synthesis and Evaluation of 1 - (Hydroxyphenyl) -1 -nonen-3-ones and Related Compounds for Antineoplastic and Antimicrobial Activities

Syntheses and Bioactivities of l-(Hydroxyphenyl)-l-Nonen-3-Ones and Related Ethers and Esters

“…Synthesis of Compounds-Compounds Ia, Ib, Ie, If, Vb, Vc, VIa-VIc, and VIIIc were prepared using the previously reported methodology (25). The remaining compounds were prepared as follows.…”

“…(E)-l-(m-Hydroxyphenyl)-l-nonen-3-one (Ic) was prepared from Id by hydrolysis with aqueous formic acid using the procedure for the formation of Ie (25). It was crystallized from petroleum ether as a colorless powder, mp 54-56', in a 73% yield.…”

Synthesis of new curcumin analogues from Claisen-Schmidt condensation

“…Various curcumin analogues have been synthesized to overcome the poor metabolic property. These compounds have been attracting much more attention, not only due to their intriguing biological activities such as cyto-toxicity [11], antimycotic [12], antitumor [13,14], antibacterial [15,16], anti-inflammatory [17], and antileishmaniatic activities [18], but also as important precursors for the synthesis of heterocyclic compounds such as pyrazolines. Generally, these compounds are prepared by Claisen-Schmidt condensation from aromatic aldehydes and ketons [19].…”

Phosphorus-Nitrogen Compounds XXIII: Oncolytic Phosphorylated Imines

“…Among those reported are phenyl nonenones (1,2), styryl ketones (3-6), a-methylene lactams and lactones (7)(8)(9), and cyclopentenones (10,ll). Each compound contains a carbonyl function with a lateral overlap between two *-bond systems to produce a molecular orbital encompassing all four atoms.…”

“…Keyphrases 0 Organometallics-triorganotin compounds, synthesis, tested for antifungal and antibacterial activity Tin-triorganotin compounds, synthesis and evaluation as antifungal and antibacterial agents 0 Antifungal agents, potential-triorganotin compounds, synthesis Antibacterials, potential-triorganotin compounds, synthesis Many biocidal applications have been found or suggested for organotin compounds (1,2). The specific organotin compounds currently used in agriculture were reviewed recently (3-5).…”