Synthesis and Determination of Acid Dissociation Constants of Bis-Acyl Thiourea Derivatives
Çağla EFEOĞLU,
Şit TİKEN,
Hayati SARI
et al.
Abstract:N,N'-((dodecane-1,12-diylbis(azanediyl))bis(carbonothioyl))bis(4-nitrobenzamide) 5 and N,N'-((dodecane-1,12-diylbis(azanediyl))bis(carbonothioyl))bis(3-nitrobenzamide) 6 as bis acyl thiourea derivatives were synthesized and their molecular structures were characterized using 1H NMR, 13C NMR, COSY, DEPT, HMQC, FT-IR, and HRMS techniques. The acid dissociation constants (pKa) of the bis-acyl thiourea derivatives 5, 6 were determined potentiometrically and spectrophotometrically. The pKa values of products 5, 6 w… Show more
This literature update is a continuation of our efforts to compile comprehensive data on research endeavors concerning acyl thioureas over the past two years.
This literature update is a continuation of our efforts to compile comprehensive data on research endeavors concerning acyl thioureas over the past two years.
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