1978
DOI: 10.1021/jo00406a021
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Synthesis and deamination of 4-aminospirohexane

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1978
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Cited by 5 publications
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“…This reaction presumably Study of the enzyme mechanism is considerably aided by mechanistic studies on analogous nonenzymic chemical reactions of appropriate model compounds. [1][2][3][4] In studies of this kind, one of the preferred factors for understanding the enzyme reactions is neighboring group participation in intramolecular reactions. Model compounds for adenosylmethionine should undergo nucleophilic attack at the sp3 carbon a to trivalent sulfur in aqueous media at moderate temperatures.…”
mentioning
confidence: 99%
“…This reaction presumably Study of the enzyme mechanism is considerably aided by mechanistic studies on analogous nonenzymic chemical reactions of appropriate model compounds. [1][2][3][4] In studies of this kind, one of the preferred factors for understanding the enzyme reactions is neighboring group participation in intramolecular reactions. Model compounds for adenosylmethionine should undergo nucleophilic attack at the sp3 carbon a to trivalent sulfur in aqueous media at moderate temperatures.…”
mentioning
confidence: 99%