Synthesis and Cytotoxicity of 2‐(2′‐Pyridyl)benzimidazole Complexes of Palladium(II) and Platinum(II)

Abstract

Compounds of type [MX 2 (Hpben)] [M ϭ Pd (X ϭ Cl), Pt (X ϭ Cl, I); Hpben ϭ 2-(2Ј-pyridyl)benzimidazole] were prepared and characterized, and the structures of the Pt derivatives were determined by X-ray crystallography. The crystals of [PtI 2 (Hpben)] consist of discrete units in which the Pt atom is coordinated to two iodine atoms and to pyridine and imidazole N atoms in a distorted square planar arrangement. The structure of the chloro derivative is similar, except that the [PtCl 2 (Hpben)] monomers are hydrogenbonded in zig-zag chains. In assays of the interactions of the Pd

Synthesis, characterization, and anticancer activities of lipophilic pyridinecarboxaldimine platinum(II) complexes

“…The nitrogen-platinum bonds of 2.002(2) Å (imine) and 2.018(2) Å (pyridine) are similar to those reported in other iminopyridine platinum systems[36][37][38][39][40][41][42][43][44][45][46][47][48]. The imine C(7)-N(8) distance is 1.291(4) Å and in the range of accepted carbon-nitrogen double bonds.…”

A luminescent bis(pyridyl)-substituted benzimidazole platinum(II) complex exhibiting an intermolecular anagostic interaction

“…The Pt-Cl bonds (Table 2) are similar in length, indicating an insignificant trans influence difference between the pyridine and imidazole rings. They are in the range 2.291 (3)-2.306 (3) Å reported for similar dichlorido(pyridin-2-ylbenzimidazole)platinum(II) complexes (Jin et al, 2014;Casas et al, 2005). The extended structure of (1) exhibits a number of interesting intermolecular interactions (see Fig.…”

“…The Pt-N(im) bond length (im is imidazole) is shorter than the Pt-N(py) bond length (py is pyridine), as is found in other platinum pyridin-2yl-substituted benzimidazole complexes (cf. Jin et al, 2014;Liu et al, 2005;Casas et al, 2005;Shavaleev et al, 2004;He et al, 2003). The Pt-Cl bonds (Table 2) are similar in length, indicating an insignificant trans influence difference between the pyridine and imidazole rings.…”

Sustainable synthesis of quinolines (pyridines) catalyzed by a cheap metal Mn(I)‐NN complex catalyst

“…The NMR analyses of the complex are consistent with its composition. In the 1 H NMR spectra, the proton resonances of the NH functionality in ligand L1 and Mn(I) complex A were shown as singlets at 12.90 [ 49 ] and 14.58 ppm, respectively, suggesting coordination between the metal center and the ligand in the complex. In the 13 C NMR spectrum, three singlets appeared at 224.0, 221.0, and 220.6 ppm for the coordinating carbonyl groups in the Mn(CO) 3 moiety of complex A .…”