Synthesis and Crystal Structure of Novel N-Acyl-N′-Dichloroacetyl-6,7-Dichloro-1,2,3,4-Tetrahydroquinoxalines Derivatives

Abstract

A two-step sequence was developed for synthesising different disubstituted 6,7-dichloro-1,2,3,4-tetrahydroquinoxalines without blocking the reactive centres. N-dichloroacetyl-6,7-dichloro-1,2,3,4-tetrahydroquinoxaline was prepared from 6,7-dichloro-1,2,3,4-tetrahydroquinoxaline and dichloroacetyl chloride giving N-acyl-N ʹ-dichloroacetyl-6,7-dichloro-1,2,3,4tetrahydroquinoxalines. The structures of all the compounds were characterised by IR, 1 H NMR, 13 C NMR, and elemental analysis. The structure was determined by X-ray crystallography.