Synthesis and crystal structure of a series of pyrazolone based Schiff base ligands and DNA binding studies of their copper complexes

Spectroscopy, Crystal and Molecular Structures of New 4-Acylpyrazolone Dinitrophenylhydrazones

“…They are synthesized easily by way of a condensation reaction between a carbonyl group (aldehydes or ketones) and an amine in a basic system with the elimination of water molecules as a by-product [3,4]. Acylpyrazolones have been reported to be a very useful chemical compound [5][6][7][8] and they form interesting Schiff bases on reaction with different amine groups by way of functional group substitution and synthetic modifications [9,10]. Their good chelating potentials towards transition metal ions have made them useful analytical reagents.…”

Crystal structure of bis-(1-(4-chlorophenyl)-3-phenyl-4-thenoyl-1H-pyrazol-5-ol-κ2O,O′)-(N,N-dimethylformamide)zinc(II), C43H31Cl2N5O5S2Zn

“…Their metal complexes have been found to display catalytic performance, biological activity and enhanced luminescence [4][5][6][7][8][9]. In recent years, we have been engaged in the preparation of the derivatives of acylpyrazolones.…”

Syntheses, crystal structure and biological evaluation of Schiff bases and copper complexes derived from 4-formylpyrazolone

“…Due to the aryl protons of phenyl rings, doublets, overlapped doublets and multiplets were observed in the region 6.9-8.0 d ppm. The 1 H NMR spectra of the ligands show singlet at 11.65 & 11.72 d ppm, which indicate that both the ligands exist in the amine-one form in the solution state [8].…”

“…Numerous Schiff base ligands of pyrazolones and their metal complexes have been reported in the literatures. Schiff bases of pyrazolones and their metal complexes are reported to be superior reagents in biological, clinical and analytical applications [6][7][8][9][10]. Pyrazolones are used in analytical chemistry for the determination and isolation of almost all metal ions due to their high extracting ability, intense color of the complex extracts and low solubility of the complex in some solvents [11].…”