Synthesis and Controlled Cargo Release of Novel Photoresponsive Polysiloxane‐Based Single‐Chain Nanoparticles
Abdalrahman Alrayyes,
Karteek Boga,
Mark Vidallon
et al.
Abstract:Herein, a novel, highly branched and photoresponsive polysiloxane is synthesized and studied. The polymer is photo‐constructed into a single‐chain nanoparticle loaded with Nile Red and Metformin. Through the photoreversible [2+2] mechanism of the polymer's pendant coumarin moieties, the nanoparticles are de‐crosslinked, and their cargo molecules released. A study of the kinetics of release is undertaken in different solvents, providing insight into the relationship between the cargo's molecular structure and t… Show more
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