“…1,2 Nucleophilic transformations of 3-aroyl-1H-pyrrolo[2,1-c] [1,4]benzoxazine-1,2,4-triones by the action of OH-and NH-mono-and NH,NH-, NH,OH-, and NH,SH-binucleophiles are convenient methods for the synthesis of carbonyl derivatives of five-and six-membered nitrogen-containing heterocycles, ensembles of such heterocycles, and fused heterocyclic systems. 1,5 .0 8,12 ]tetradecane system 7,8 E, respectively (Scheme 1). During continuing studies on analogous transformations, we have now examined the reaction of pyrrolobenzoxazinetriones with a spiro heterocyclic enamine containing an additional functional amide group NH 2 -substituted 2-(3,3-dimethyl-8-oxo-2-azaspiro [4.5]deca-6,9-dien-1-ylidene)acetamides.…”