Synthesis and characterization of thermo- and pH-responsive bacterial cellulose/acrylic acid hydrogels for drug delivery

Synthesis and characterization of new shellac–hydroxypropylmethylcellulose composite for pharmaceutical applications

“…Literature sources is abundant with examples of number of pH-responsive polymeric materials that have been prepared from synthetic as well as natural sources and used in controlled release of drugs [11][12][13][14][15][16]. However, it is to be noted that appropriate designing of a new pH-responsive matrix always requires maintaining the correlation between material cross-linking properties and swelling characteristics [5].…”

“…In recent years, natural polymers such as starch, cellulose, alginate, tamarind gum, okra gum, chitosan, xylan, etc., are gaining importance in biomedical field of research primarily due to their availability, sustainability and low level of toxicity [1][2][3][4][5]. Natural polymers are also preferred over synthetic one because of organized molecular structure and biocompatible characteristics [3,6].…”

pH Sensitive Hydrogel Based on Poly(Acrylic Acid) and Cellulose Nanocrystals

“…From the hydrogel spectrum, the bands at 1409 and 1450 cm -1 are attributed to C-OH bending vibration of PAA. The absence of C=C stretching from hydrogel spectrum indicates the polymerization of acrylic acid into poly(acrylic acid), an indication supported by the finding that irradiation of acrylates with electrons leads to the curing of the polymer by the formation of radicals that initiate the polymerization and crosslinking reaction (Mohd Amin et al 2012;Rahimi et al 2012;Scherzer et al 1997). …”

“…This indicates a favorable interaction between the matrix and filler in the hydrogel structure leading to its increased stability. CNC/ PAA hydrogel showed even higher thermal stability as compared to cellulose/PAA hydrogel due to the presence of CNC in hydrogel network which had resulted in a more structured hydrogel (Bayramgil 2008;Bera et al 2013;Cha et al 2012;Mohd Amin et al 2012).…”

Study on swelling behaviour of hydrogel based on acrylic acid and pectin from dragon fruit

“…The gel content increased in proportion to radiation dose up to 30 kGy. At a higher dosage, the irradiation leads to the radiolysis of water, resulted in the production of electrons, hydroxyl radicals, hydrogen atoms and reactive species, which likely led several reactive sites on the AA to be cross-linked [8]. However, when irradiation dose exceeded 30 kGy, both homopolymerization and grafting of AA are terminated [9].…”