Abstract:[18F]Fluoroestradiol ([18F]FES), an estrogen analog, may be used in Positron Emission Tomography (PET) for evaluation of the tumor cell receptor profile in a noninvasive way, which is an important factor for determining the therapy to be used, disease staging, prognosis and response to therapy in breast cancer. [18F]FES is a new radiopharmaceutical and does not have an official monograph in any pharmacopeia until now. Therefore, the objective of this work was the optimization of the [18F]FES automatic synthesi… Show more
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