Synthesis and characterization of segmented polyurethanes

Abstract

Segmented polyurethanes (SPUs) based on PEG, PTMC and PLLA as macrodiols, HDI as diisocyanate and BDO as chain extender were synthetized and characterized with respect to composition, thermal and dynamical mechanical properties. The SPUs are heterogeneous and the thermal events observed in DSC and DMA analyses are related to the macrodiols components, being affected by the global composition.

Poly(trimethylene carbonate)‐b‐poly(ethylene glycol) diblock copolymer micelles for hydrophobic drug delivery: The effect of hydrophilic/hydrophobic segment length on micellar properties and drug loading

“…With the same mPEG block, the increase of the EO/TMC ratio or the decrease of the M n ,PTMC leads to the decrease of T g and T C values. Typically, the T g of PEG and PTMC are at about −65, −15°C, respectively 40 . And all the PTMC‐PEG copolymers exhibit a T g at the range of −50.1 to −38.9°C, which is between those of the two homopolymers, indicating that mPEG and PTMC segments in the copolymer are compatible in the amorphous region.…”

“…Furthermore, the dispersity Typically, the T g of PEG and PTMC are at about À65, À15 C, respectively. 40 And all the PTMC-PEG copolymers exhibit a T g at the range of À50.1 to À38.9 C, which is between those of the two homopolymers, indicating that mPEG and PTMC segments in the copolymer are compatible in the amorphous region. Furthermore, the T m and ΔH m increase as the ratio of EO/TMC increase.…”