Synthesis and characterization of Se doped Fe3O4 nanoparticles for catalytic and biological properties

Abstract

In this study, Se-doped Fe3O4 with antibacterial properties was synthesized using by a coprecipitation method. The chemistry and morphology of the Se doped Fe3O4 nanocomposite were characterized by energy-dispersive X-ray spectroscopy, field-emission scanning electron microscopy, X-ray diffraction, vibrating sample magnetometry, and Brunauer–Emmett–Teller spectroscopy. The antibacterial activity of the Fe3O4/Se nanocomposite was examined against G+ (Gram-positive) and G− (Gram-negative) bacteria, in the order Staphylococcusaureus, Staphylococcussaprophyticus, Pseudomonasaeruginosa, Klebsiellapneumonia, and Escherichiacoli, which are the most harmful and dangerous bacteria. Fe3O4/Se, as a heterogeneous catalyst, was successfully applied to the synthesis of pyrazolopyridine and its derivatives via a one-pot four-component reaction of ethyl acetoacetate, hydrazine hydrate, ammonium acetate, and various aromatic aldehydes. Fe3O4/Se was easily separated from the bacteria-containing solution using a magnet. Its admissible magnetic properties, crystalline structure, antibacterial activity, mild reaction conditions, and green synthesis are specific features that have led to the recommendation of the use of Fe3O4/Se in the water treatment field and medical applications. Direct Se doping of Fe3O4 was successfully realized without additional complicated procedures.

The Promise of Metal-Doped Iron Oxide Nanoparticles as Antimicrobial Agent

“…This modification could potentially enhance the antimicrobial activity of doped-IONPs . Ahghari et al (2013) also demonstrated that doped-IONPs yield more than bare IONPs. However, careful consideration of the dopant type and concentration is necessary to achieve desired nanoparticles without compromising their functionality …”

“…Different Biomedical Applications of Doped-IONPs. Doped-IONPs have diverse applications in various fields of biomedicine�for instance, in MRI, 78,79 visualization and diagnostics, 80 cancer therapy with magnetic hyperthermia, 81 photodynamic therapy, 82 development of biosensors, 83 environmental remedies, 31 and tissue engineering 84,85 -(Figure 2). Recently, experimental biomedical imaging field has gotten more focused on the fabrication of novel contrast agents with multimodal and versatile features of doped-IONPs.…”

“…118 Doped-IONPs and bare IONPs shared similar mechanism of actions from generating ROS for disrupting the bacterial DNA and membrane, leading to cell death eventually. 25,[28][29][30][31][32]34,36,51,52,116…”

“…Similarly, the insertion of foreign metal particles into IONPs alter their physicochemical, as well as biological, electrical, and optical, properties and improve performance compared to bare IONPs . IONPs are doped with several metals, and their oxides, such as Ni, , Cu, , Co, Zn, , Se, Mo, Au, , ZnO, , CuO, exhibit antimicrobial activity toward pathogenic bacteria.…”

Regulation of saturation magnetization of magnetite by doping with group III elements

“…33 In contrast, Se doping greatly decreases the M S of Fe 3 O 4 nanoparticles. 34 Nonmagnetic group III elements (Al, Ga, and In) have a similar atomic radius to Fe and may replace Fe 3+ in Fe 3 O 4 after doping and thus regulate the M S of Fe 3 O 4 nanoparticles. Here, by accurate hybrid density functional computation, the doping behavior of group III elements in Fe 3 O 4 and the doping effects on the M S of Fe 3 O 4 were carefully studied.…”