Synthesis and characterization of polyamidoamine dendrimers surface-functionalized with bromotricarbonylpyridyliminerhenium(I) units

Zhao, Xinxin; Yan, Yaw Kai; Chu, Chit‐Kay

doi:10.1016/j.jorganchem.2006.08.094

Cited by 4 publications

(4 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The authors have reported the synthesis of Pt(II), Pd(II), Cu(II), and Hg(II) complexes with N-[2-(pyridine-2-ylmethylidene)amino)ethyl]acetamide showing moderate to low activities against human leukaemia (MOLT-4) and breast cancer (MCF-7), and no activity against non-cancerous Chang Liver cell lines. 21 , 22 More recently the importance of ruthenium metallodendrimers was nicely pointed out using either arene ruthenium carbosilane dendrimers, 23 arene ruthenium metallacages pyrenyldendrimers, 24 and ruthenium-PTA phosphorus dendrimers. 25 Another example was reported by Sadler's group consisting of the synthesis of different organometallic osmium arene complexes with substituted phenylazopyridines as chelating ligands.…”

Section: Acs Paragon Plus Environmentmentioning

confidence: 99%

“…Following Chu and collaborators, several works were carried out on the synthesis and cytotoxicity of transition metal complexes with Schiff base ligands. The authors have reported the synthesis of Pt(II), Pd(II), Cu(II), and Hg(II) complexes with N -[2-(pyridine-2-ylmethylidene)amino)ethyl]acetamide showing moderate to low activities against human leukemia (MOLT-4) and breast cancer (MCF-7), and no activity against noncancerous Chang Liver cell lines. , …”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Original Multivalent Gold(III) and Dual Gold(III)–Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents

et al. 2017

View full text Add to dashboard Cite

Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II). The complexation of the dendrimer with Au(III), leading to 1G3-[Au][AuCl], strongly increased the antiproliferative activities against both KB and HL-60 tumoral cell lines, showing ICs in the low nanomolar range. It can be noticed also that this gold conjugated phosphorus dendrimer displayed low activity on the quiescent cell line EPC versus its potent antiproliferative activity against actively dividing cells. In order to evaluate the potential synergistic effect between Au(III) and Cu(II) and the influence of the number of Au(III) moieties on the surface of dendrimer against the proliferative activities, nine other original dendrimers with several surface modifications have been prepared. Whatever the number of Au(III) moieties introduced on the surface of dendrimers, all the dendrimers prepared displayed similar potency (nanomolar range) to 1G3-[Au][AuCl] against KB and HL60. In marked contrast synergistic effects on the antimicrobial activity of some of these phosphorus dendrimers are observed when both Au(III) and Cu(II) are present on the dendritic structure.

show abstract

Section: Acs Paragon Plus Environmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Original Multivalent Gold(III) and Dual Gold(III)–Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Solvents were dried and distilled under nitrogen before use. The ligand [G0-Py 4 ] (4L) was prepared according to methods reported previously [13]. All syntheses were carried out in a purified nitrogen or argon atmosphere, employing standard Schlenk techniques.…”

Section: Methodsmentioning

confidence: 99%

“…The ligand 4L was prepared through a condensation reaction using first generation PAMAM (G0) and pyridine-2-carboxaldehyde as described in our previous paper [13].…”

Section: Preparation Of [G0-py 4 ] (4l)mentioning

confidence: 99%

Synthesis and cytotoxic activities of chloropyridylimineplatinum(II) and chloropyridyliminecopper(II) surface-functionalized poly(amidoamine) dendrimers

Zhao

Loo

Lee

et al. 2010

Journal of Inorganic Biochemistry

Self Cite

View full text Add to dashboard Cite

Novel nickel complexes with hyperbranched structure: Synthesis, characterization and performance in ethylene oligomerization

Wang

Lin

et al. 2016

Inorganica Chimica Acta

View full text Add to dashboard Cite

Synthesis and characterization of polyamidoamine dendrimers surface-functionalized with bromotricarbonylpyridyliminerhenium(I) units

Cited by 4 publications

References 27 publications

Original Multivalent Gold(III) and Dual Gold(III)–Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents

Original Multivalent Gold(III) and Dual Gold(III)–Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents

Synthesis and cytotoxic activities of chloropyridylimineplatinum(II) and chloropyridyliminecopper(II) surface-functionalized poly(amidoamine) dendrimers

Novel nickel complexes with hyperbranched structure: Synthesis, characterization and performance in ethylene oligomerization

Contact Info

Product

Resources

About