Synthesis and characterization of novel antimicrobial cationic polyelectrolytes

Čakmak, İsmail; Ulukanlı, Zeynep; Tuzçu, Mehmet; Karabuğa, Şemistan; Genctav, Kenan

doi:10.1016/j.eurpolymj.2004.06.004

Cited by 58 publications

(43 citation statements)

References 10 publications

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“…Treatment with 10% (v/v) complex beads for 5 min completely eliminated the test microorganisms. The antimicrobial efficiency of the SA-TSA complex beads is higher than those of other insoluble antimicrobial polymers such as crosslinked polystyrenes with quaternary ammonium [7] and cationic polyelectrolytes [17].…”

Section: Antimicrobial Activity Of Sa-tsa Complex Beadsmentioning

confidence: 99%

Preparation of alginate–quaternary ammonium complex beads and evaluation of their antimicrobial activity

Kim¹,

Kim²,

Lee³

et al. 2007

International Journal of Biological Macromolecules

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Section: Antimicrobial Activity Of Sa-tsa Complex Beadsmentioning

confidence: 99%

Preparation of alginate–quaternary ammonium complex beads and evaluation of their antimicrobial activity

Kim¹,

Kim²,

Lee³

et al. 2007

International Journal of Biological Macromolecules

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“…In addition, Cakmak et al 38 utilized benzyl amine and epichlorhydrin to synthesize a series of polyelectrolytes with various molecular weights and evaluated their antimicrobial activity against bacteria, yeast and fungi. It is suggested that longer polymer chains and higher density of positive charges could impose more considerable inhibition on the growth of the bacteria and yeast with MICs 2.5 and 0.625 μg ml − 1 , respectively.…”

Section: Topological Designsmentioning

confidence: 99%

Antimicrobial cationic polymers: from structural design to functional control

Yang

Cai

Huang

et al. 2017

Polym J

207

174

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Antimicrobial cationic polymers mainly contain two functional components: the cationic groups and the hydrophobic groups. The antimicrobial activity is influenced by the type, amount, location and distribution of these two components. This review summarizes the designs and syntheses of antimicrobial cationic polymers by controlling the above two factors. It involves the structural designs from primary to secondary structures, from covalent to noncovalent syntheses and from bulk to surface. Furthermore, it will discuss how to advance structural designs toward functional controls for optimizing the antimicrobial performances and biocompatibility of antimicrobial cationic polymers. It is anticipated that this review will provide some guidelines for developing molecular engineering of antimicrobial cationic polymers with tailor-made structures and functions.

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“…(1) Polymers with quaternary nitrogen atoms [60] that can exist in different structures, that is, aromatic or heterocyclic structures [59], cationic conjugated polyelectrolytes [58], quaternary nitrogen atoms within the main chain [60], block copolymers [61], and synthetic and dendrimeric peptides [62, 63]. All of them were shown to be effective against a variety of microorganisms based on the exposure of its quaternary ammonium group.…”

Section: Need Of New Antifungal Agentsmentioning

confidence: 99%

CandidaInfections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

Spampinato

Leonardi

2013

BioMed Research International

309

261

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The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or immunocompromised. Candida infections can be superficial or invasive. Superficial infections often affect the skin or mucous membranes and can be treated successfully with topical antifungal drugs. However, invasive fungal infections are often life-threatening, probably due to inefficient diagnostic methods and inappropriate initial antifungal therapies. Here, we briefly review our current knowledge of pathogenic species of the genus Candida and yeast infection causes and then focus on current antifungal drugs and resistance mechanisms. An overview of new therapeutic alternatives for the treatment of Candida infections is also provided.

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Synthesis and characterization of novel antimicrobial cationic polyelectrolytes

Cited by 58 publications

References 10 publications

Preparation of alginate–quaternary ammonium complex beads and evaluation of their antimicrobial activity

Preparation of alginate–quaternary ammonium complex beads and evaluation of their antimicrobial activity

Antimicrobial cationic polymers: from structural design to functional control

CandidaInfections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

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