Synthesis and Characterization of Novel Schiff's Bases from Ethylenediamine Tetraacetic Acid Derivatives.

Abstract

A novel Schiff's base have been synthesized by reaction between ethylenediaminetetraacetic acid (EDTA) derivatives with (2-methoxyaniline, 4-bromoaniline, 4-amino antipyrine) are successfully prepared to obtain six Schiff's base through the reaction of the aldehyde group with compounds containing the amine group as a catalyst glacial acetic acid in ethanol under reflux in good yield (78–92%), the prepared compounds were characterized by were synthesized and characterized by (FT-IR) and 1HNMR, 13C spectroscopy, elemental analysis. The aim of this study is to use cheap EDTA to synthesize Schiff bases, which are thought to have effective biologic and antibacterial properties.