Synthesis and characterization of nickel oxide hollow spheres–reduced graphene oxide–nafion composite and its biosensing for glucose

Three-dimensional roselike α-Ni(OH)2 assembled from nanosheet building blocks for non-enzymatic glucose detection

“…As shown in Table 1, it could be clearly seen that the Ni(OH) 2 -RS/GCE offered reasonable sensitivity and detection limit, but the linear range of the Ni(OH) 2 because it consisted of twisted nanosheets as a secondary building block, which result in the active surface domains being easily accessed by glucose. Hence, the catalytic efficiency was greatly enhanced.…”

“…As stated by the global burden of disease (GBD), the global prevalence of diabetes was 346 million in 2008, and this quantity will continue to increase in the future [2,3]. According to population studies, the top five nations in terms of the number of diabetic patients are China (92.4 million), India (50.8 million), US (26.8 million), Russia (9.6 million) and Brazil (7.6 million), spanning developing and developed countries and covering diverse geographic areas [4,5].…”

“…Over the past few years, considerable efforts have been devoted to the development of alternative method for the detection of glucose, such as high performance liquid chromatography method [6], colorimetry [7], chemiluminescence [8], electrochemiluminescence [9,10], and electrochemical sensors [2,[11][12][13]. Among these techniques, the electrochemical sensors have been recognized as one of the most convenient and promising approaches due to its simplicity, rapid response, high sensitivity and ease of use [11,14,15].…”

“…For example, platinum, gold and alloy have been broadly developed to detect glucose [17]. However, these noble metals-based sensors have displayed some drawbacks, such as: (1) the glucose usually exhibit sluggish voltammetric response on these electrodes due to their low electroactivity and high oxidation overpotential; (2) other electroactive compounds such as ascorbic acid (AA) and uric acid (UA) can be oxidized in the similar potential and results in poor selectivity [18]; (3) the surfaces of noble metals are easily poisoned by the adsorbed intermediates or chloride. Therefore, the search for novel material recipes and appropriate architectures is the key step in the fabrication of highly sensitive non-enzymatic glucose sensors.…”

Optimum Copper-Palladium Catalyst from a Combinatorial Library for Sensitive Non-Enzymatic Glucose Sensors

“…This experiment was performed under flowing conditions with a flow rate in the range of milliliters per hour that allows quasi-stationary conditions. The use of a flow cell conferred the possibility to investigate the online glucose monitoring behavior of the sensing material (e.g., environmental monitoring, blood glucose concentration [11,36]). The measurement without the addition of glucose is shown as background level.…”