2017
DOI: 10.1002/slct.201700878
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Synthesis and Characterization of Multifunctional Interpenetrating Polymer and Its Applications in Protein Adsorption and Magnetite Loading

Abstract: In this study, we prepared interpenetrating polymers as nanocarrier systems for protein adsorption and superparamagnetic iron oxide nanoparticles (Fe3O4 NPs) loading. Interpenetrating polymer network (IPN) nanogels composed of crosslinked poly (N‐isopropylacrylamide) (PNIPAM) and poly (acrylic acid) (PAA) were firstly prepared, which possessed both pH and thermo‐responsive properties. On the one hand, the model protein (bull serum albumin (BSA)) was loaded into PNIPAM/PAA IPN nanogels. The effect of PAA conten… Show more

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Cited by 4 publications
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“…In particular, poly(N‐isopropylacrylamide) (PNIPAM)‐based IPN microgels exploit the temperature‐sensitivity of PNIPAM conformation (swelling/shrinking of the network) and add, in most cases, pH‐sensitive properties. They offer many perspectives for technological applications, mainly in biomedical field (e. g. drug delivery, soft robotics, engineered tissues) . Moreover, they are used as model systems in soft matter chemistry and physics, thanks to their phase behavior (volume phase transition) and colloidal properties .…”
Section: Introductionmentioning
confidence: 99%
“…In particular, poly(N‐isopropylacrylamide) (PNIPAM)‐based IPN microgels exploit the temperature‐sensitivity of PNIPAM conformation (swelling/shrinking of the network) and add, in most cases, pH‐sensitive properties. They offer many perspectives for technological applications, mainly in biomedical field (e. g. drug delivery, soft robotics, engineered tissues) . Moreover, they are used as model systems in soft matter chemistry and physics, thanks to their phase behavior (volume phase transition) and colloidal properties .…”
Section: Introductionmentioning
confidence: 99%