Synthesis and characterization of inclusion complex of -cyclodextrin and triazole picrate

Abstract

ABSTRACT. Inclusion complex between 3-amino-1,2,4-triazole picrate and β-cyclodextrin was synthesized in order to increase the picrate solubility. The complex was obtained by co-precipitation method and its stoichiometry is 1:1 (guest–host). The structure of picrate and complex has been established by UV, X-ray diffractometry powder spectra, TGA, DSC, IR, 1H NMR, and 13C NMR. The influence of the effect of pH on the complexation has been discussed. The value of apparent formation constant is 1.2 x 104.
 
 KEY WORDS: Amino triazole, Picrate, Inclusion complex, pH
 Bull. Chem. Soc. Ethiop. 2023, 37(4), 973-982. 
 DOI: https://dx.doi.org/10.4314/bcse.v37i4.13