Synthesis and characterization of gold glyconanoparticles functionalized with sugars of sweet sorghum syrup

Abstract

Gold glyconanoparticles were synthesized by a simple, rapid, and eco-friendly method by using sweet Sorghum syrup for application in biomedicine and biotechnology. The nanostructures of the prepared gold nanoparticles were confirmed by using UV-visible absorbance, TEM, SAED, FTIR, EDAX, XRD, and photoluminescence analyses. The formation of gold nanoparticles at both room and boiling temperatures and kinetics of the reaction were monitored by UV-visible spectroscopy and TEM studies. TEM analysis revealed that the obtained nanoparticles were mono-dispersed and spherical in shape with an average particle size of 7 nm. The size of the nanoparticles was influenced by the concentration of Sorghum syrup. The presence of elemental gold was confirmed by EDAX analysis. Based on the FTIR analysis, it was observed that the sugars present in the Sorghum syrup possibly acts as capping agents. The zeta potential analysis revealed that the glyconanoparticles were negatively charged with a potential of -25 mV. The XRD and SAED patterns also suggest that the nanoparticles were crystalline in nature and these particles were found to exhibit visible photoluminescence. Fructose and glucose present in sweet Sorghum syrup were demonstrated as responsible sugars for the reduction of gold ions, and sucrose stabilized the formed nanoparticles. The proposed mechanism for the formation and stabilization of gold glyconanoparticles is based on the phenomenon of "macromolecular crowding." This is the first report on the use of sweet Sorghum syrup for the green synthesis of gold glyconanoparticles at both room and boiling temperatures.

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Rapid synthesis of gold nanostructures with cyclic and linear ketones

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Silver glyconanoparticles functionalized with sugars of sweet sorghum syrup as an antimicrobial agent

“…[25,26]. In continuation to our earlier study on the preparation of gold glyconanoparticles using sweet sorghum syrup [27], and the importance of glyconanoparticles from a biotechnological and biomedical perspective, we developed a simple and rapid green synthetic approach for the preparation of silver glyconanoparticles functionalized with sugars of sweet sorghum syrup and the application of these silver glyconanoparticles as an antimicrobial agent. The advantage of using sweet sorghum syrup is that it is a low-cost and renewable biomaterial with sugars, minerals, vitamins and proteins in which sugars acting as reducing and capping ligands during the formation of silver glyconanoparticles without the requirement of additional chemical reagents.…”