Synthesis and Characterization of Donor-Functionalized N,S-Compounds Containing the ortho-Aminothiophenol Motif

Abstract

D o n o r-F u n c t i o n a l i z e d N , S-C o m p o u n d s w i t h t h e A m i n o t h i o p h e n o l M o t i f

Chiral halogenated Schiff base compounds: green synthesis, anticancer activity and DNA-binding study

“…As in the literature reported, the most common synthetic route for synthesis Schiff bases is the reaction of aldehydes and ketones with primary amines. The reaction is generally carried out by refluxing the carbonyl compounds and amines in organic solvents by separating water as formed with an azeotroping agent or by anhydrous Na2SO4 and MgSO4 [ [14], [15], [16], [17], [18]]. The replacement of volatile organic solvents in organic reaction processes is an important green chemistry goal.…”