Synthesis and Characterization of Copper-Doped Zinc Selenide Quantum Dots as Fluorescence Probes for Sparfloxacin

Abstract

Copper-doped zinc selenide quantum dots modified with mercaptopropionic acid were prepared. The fluorescence quenching of the quantum dots was directly proportional to sparfloxacin concentration. A novel method was established to determine sparfloxacin using the copper-doped zinc selenide quantum dots as fluorescent probes. The interaction between the quantum dots and sparfloxacin was investigated by fluorescence and absorption spectroscopies. A linear relationship was obtained between the quenched fluorescence and sparfloxacin concentration from 1 × 10 À6 to 1.8 × 10 À5 moles per liter in KH 2 PO 4 -Na 2 HPO 4 buffer at pH 7.5 using copper-doped zinc selenide quantum dots at 2.9 × 10 À6 moles per liter. The limit of detection for sparfloxacin was 2.4 × 10 À9 moles per liter. The method was used for the determination of sparfloxacin in tablets and water with satisfactory results.

Theoretical and experimental investigation of doping M in ZnSe (M = Cd, Mn, Ag, Cu) clusters: optical and bonding characteristics

“…Nanocrystals (NCs), such as CdSe, CdTe, ZnSe, have been investigated because of their unique dimensions and size‐dependent physicochemical properties . The photoluminescence (PL) of doped ZnSe NCs can be tuned by changing the type and amount of impurity, and this property has attracted increasing attention . Mn‐ and Cu‐doped ZnSe NCs have been synthesized using aqueous and oil phase methods.…”