Synthesis and characterization of Au:ZnO (core:shell) nanoparticles via laser ablation

Rashid, Taha M.; Nayef, Uday M.; Jabir, Majid S.; Mutlak, Falah A.-H.

doi:10.1016/j.ijleo.2021.167569

Cited by 79 publications

(26 citation statements)

References 30 publications

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“…Zinc oxide (ZnO) and Au@ZnO core/shell were synthesized by pulsed laser ablation of pure granulated zinc metal in deionized water and chloroauric acid, respectively, as described in the method of Rashid and his coworkers [ 39 ]. The target was put in the bottom of a glass vessel filled with 3 mL of the used liquid media.…”

Section: Methodsmentioning

confidence: 99%

Inhibition of Staphylococcus aureus α‐Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite

Jabir

Rashid

Nayef

et al. 2022

Bioinorganic Chemistry and Applications

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Nanoparticles of gold with zinc oxide (Au@ZnO NPs) were prepared by laser ablation and then capped with curcumin nanoparticles (Cur-Au@ZnO NPs). The synthesized NPs were characterized using different techniques, including transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), UV-visible spectroscopy, and X-ray diffraction. In addition, the ability of NPs as a promising antibacterial agent was tested against Staphylococcus aureus through the agar well diffusion method and AO/EtBr staining assay. The results showed that the prepared nanoparticles (Cur-Au@ZnO) served as an antibacterial agent and can destroy the bacterial cells by losing the cell wall integrity and penetrating the cytoplasmic membrane. Moreover, the findings confirmed the role of the formed NPs in attenuation of the adherence and invasion of S. aureus to rat embryonic fibroblast (REF) cells. Furthermore, the activity of Cur-Au@ZnO NPs against the S. aureus α-hemolysin toxin was evaluated using the western blot technique, using human alveolar epithelial cells (A549), and through histopathology examination in a mouse model. In conclusion, the built Cur-Au@ZnO NPs can be used as a potential antibacterial agent and an inhibitor of α-hemolysin toxin secreted by S. aureus. These NPs may offer a new strategy in combating pathogen infections and in the future for biomedical and pharmaceutical applications.

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Section: Methodsmentioning

confidence: 99%

Inhibition of Staphylococcus aureus α‐Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite

Jabir

Rashid

Nayef

et al. 2022

Bioinorganic Chemistry and Applications

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“…The tumoricidal activity of macrophage in the peritoneal cavity was done according to [36]. briefly, GNPs, Silica-GNPs was given at a dose of 20 µg/mice for three days.…”

Section: In Vivo Tumoricidal Activity Of Macrophage Cellmentioning

confidence: 99%

Gold and silica gold nanoparticles enhances macrophages kill tumor cells via granzyme-perforin pathway

Mannoush

Jabir

Thaker

2022

ijhs

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The goal of the study was to see if gold nanoparticles (GNPs) and silica gold nanoparticles (Si-GNPs) could help cancer cells phagocytes. Scanning electron microscopy (SEM) and Ultraviolet-visible spectroscopy (UV-VIS) absorptions were used to characterize the nanomaterial's. In both in vitro and in vivo conditions, the GNPs and Si-GNPs enhanced macrophage phagocytosis capabilities, resulting in the annihilation of cancer cells. The effect of GNPs and Si-GNPs in Tumor necrosis factor alpha (TNF-α) and Interleukin-8 (IL-8) levels was investigated in Ehrlich tumor cells using Enzyme linked immunosorbent assay (ELISA) assay. The results shows the ability of GNPs and Si-GNPs to increase TNF-α and IL-8 in treated Ehrlich Ascites Carcinoma (EAC). It was found that the most effect was in Si-GNPs group. GNPs and Si-GNPs enhance phagocytic cells for increased granzyme and perforin-mediated cancer cell death on a regular basis. Overall, the findings showed that GNPs and Si-GNPs improved phagocytic cell activation, which might be employed as a promising technique for managing cancer cells by enhancing cell death via a Granzyme-perforin dependent mechanism.

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“…Zinc oxide is a semiconductor with a wide bandgap of 3.37 eV and a large exciton binding energy of 60 meV at room temperature, including excellent chemical and thermal stability [3], safe and biocompatible [4]. It was established to initiate in assorted applications such as UV photodetectors [5] optoelectronics [6], solar cells [7], laser technology [8], light-emitting diodes (LEDs) [9], surface acoustic wave's device [10], antimicrobial and antifungal activity [11], luminescent, gas sensor devices [12], optical coatings [13], chemical sensor [14], acaricidal antidiabetic, photonic crystals [15], gene delivery [16], and photovoltaics [17] Moreover, it has also exhibited better performance to eliminate organic pollutants in water such as methylene blue (MB), acridine orange, rhodamine B, methylene orange, and polyvinyl alcohol in aqueous solution [1][2][13][14]. Zinc oxide nanoparticles (ZnO-NPs) have been synthesized using different techniques.…”

Section: Introductionmentioning

confidence: 99%

“…Zinc oxide nanoparticles (ZnO-NPs) have been synthesized using different techniques. The synthesis techniques are hydrothermal method [12], co-precipitation [18], pulsed laser deposition (PLD) [7], sol-gel method [19], microwave-assisted combustion, and solid-state reaction [20], Pulsed laser ablation in liquids (PLAL) [15]. Among the above techniques, coprecipitation is a promising option for the synthesis with large-scale production of zinc oxide nanoparticles (ZnO-NPs) [10].…”

Section: Introductionmentioning

confidence: 99%

Synthesis Europium (Eu3+) Doped Zinc Oxide Nanoparticles via the Co-Precipitation Method for Photocatalytic Applications

Barsisa¹,

Belay²,

Beyene³

et al. 2022

Nano BioMed ENG

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Synthesis and characterization of Au:ZnO (core:shell) nanoparticles via laser ablation

Cited by 79 publications

References 30 publications

Inhibition of Staphylococcus aureus α‐Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite

Inhibition of Staphylococcus aureus α‐Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite

Gold and silica gold nanoparticles enhances macrophages kill tumor cells via granzyme-perforin pathway

Synthesis Europium (Eu3+) Doped Zinc Oxide Nanoparticles via the Co-Precipitation Method for Photocatalytic Applications

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