Synthesis and characterization of antimony (III) heteroleptic derivatives having oxygen, nitrogen and sulfur containing organic moieties with their antibacterial and antioxidant activities

Syntheses and characterization of novel antimony (III) and bismuth (III) derivatives containing β‐enamino ester along with antimicrobial evaluation, DFT calculation, and cytotoxic study

“…[31] The melting point of the synthesized complexes was determined in sealed capillaries. The FT-IR spectra were recorded using KBr pellets on a PerkinElmer-Spectrum RX-IFTIR at 4000-400 cm −1 frequency, while 1 H and 13 C NMR spectra were recorded in CDCl 3 solution on JEOL resonance with tetramethylsilane as an internal reference. The mass spectra of the derivatives were obtained using APCI mass spectrometry.…”

“…Spectral studies 1 H and 13 C NMR were carried out at MNIT, Jaipur, while IR was carried out at the sophisticated analytical instrument facility (SAIF) of Panjab University, Chandigarh.…”

“…T A B L E 3 13 C NMR spectral data (δ) ppm of antimony (III) and bismuth (III) derivatives. Following conclusions can be drawn from the observation:…”

Insights into the Antimicrobial Potential of Dithiocarbamate Anions and Metal-Based Species

“…Their antimicrobial properties were screened against two Gram-negative bacteria (E. coli and P. aeruginosa) and two fungal strains (A. flavus and A. niger); the results indicated the incorporation of antimony enhanced the inhibitory effect compared to the free ligand owing to the increased lipophilic character of the metal chelate that aids the permeation of the compounds through the lipid layer of cell membranes [112]. Later, Beniwal et al further investigated the antimicrobial activities of antimony(III) dithiocarbamates also containing substituted oxime molecules, that is, PhSb[R(R )C=NO](L 10 ) [113] and Sb[R(R )C=NO] 2 (L 10 ) [114], and some antimony(V) species, Ph A broader range of main group elements was investigated in a study of M(L 82 ) 3 , where M(III) = Ga, In, As, Sb, and Bi, which were subjected to antibacterial assays against ten American Type Culture Collection (ATCC) bacterial strains and ten multiresistant clinical isolated strains, including four extended-spectrum β-lactamase producing E. coli strains, one methicillin resistant S. epidermidis strain, three methicillin-resistant S. haemolyticus strains, and one methicillin-resistant S. simulans strain [37]. Overall the indium(III) species demonstrated the greatest antibacterial activities against the evaluated bacterial strains, a result correlated with computational studies that showed In(L 82 ) 3 possessed better stability than the other congeners thus promoted its transport to the biological target site in the bacterial cell.…”

“…The PhSb[R(R )C=NO](L 10 ) compounds showed greater antibacterial effects towards B. subtilis while PhSb[(C 6 H 4 OH-4)HC=NO](L 10 ) exhibited marked activities against both bacteria. On the other hand, [(C 6 H 4 Me-4)C(Me)=NO] 2 Sb[S 2 CN(L 10 )] was the most active among the series in[114] while in the case of Ph 3 Sb[R(R )C=NO](L 18 )[115], when R = Me, R' = C 6 H 4 Cl-4; and R = H, R' = C 6 H 4 OH-4, the compounds showed greater antibacterial activity towards B. subtilis.…”