Synthesis and Characterization of Aminopropyltriethoxysilane-Polydopamine Coatings

Abstract

Polydopamine coatings are of interest due to the fact that they can promote adhesion to a broad range of materials and can enable a variety of applications. However, the polydopamine-substrate interaction is often noncovalent. To broaden the potential applications of polydopamine, we show the incorporation of 3-aminopropyltriethoxysilane (APTES), a traditional coupling agent capable of covalent bonding to a broad range of organic and inorganic surfaces, into polydopamine coatings. High energy X-ray photoelectron spectroscopy (HE-XPS), conventional XPS, near-edge X-ray absorption fine structure (NEXAFS), Fourier transform infrared-attenuated total reflectance (FTIR-ATR), and ellipsometry measurements were used to investigate changes in coating chemistry and thickness, which suggest covalent incorporation of APTES into polydopamine. These coatings can be deposited either in Tris buffer or by using an aqueous APTES solution as a buffer without Tris. APTES-dopamine hydrochloride deposition from solutions with molar ratios between 0:1 and 10:1 allowed us to control the coating composition across a broad range.

Oxidative Polymerization of Dopamine: A High-Definition Multifunctional Coatings for Electrospun Nanofibers - An Overview

“…A coating thickness of ~1 μm was possible to achieve by this method by varying dopamine:PEI ratio and reaction time. Similarly, Knorr et al reported the use of APTES as organic base for the preparation of pDA-silicate composite films in both neutral and basic pH conditions [30]. In both pH, the coating thickness and coating speed depend on APTES:dopamine ratio.…”

In Situ Infrared Spectroscopic Monitoring and Characterization of the Growth of Polydopamine (PDA) Films

“…In this article, we will focus on polydopamine (PDA), an apparent dark, insoluble material as a functional thin film material for biosensor and biomedical applications. PDA is in particular interesting because (i) it can be synthesized by alkali‐induced autoxidation of dopamine; (ii) it shows excellent adhesive properties on almost every type of materials such as metals, semi‐conductors, polymers, or even nanoparticles; (iii) it exhibits excellent biocompatibility because of the similarity to melanin (eumelanin) occurred in nature; (iv) it can be incorporated with other functional groups (e.g., SH or NH 2 ) because chemical structures such as catechol, amine, or imine are available . Due to this multifold potential of PDA, a great number of investigations have been carried out to study the influence of experimental parameters on the film structural and growth/polymerization mechanisms of PDA particles and thin films in the past few years.…”

Probing polydopamine adhesion to protein and polymer films: microscopic and spectroscopic evaluation

“…The mussel adhesive-inspired polydopamine (PD) appears to be an ideal biomaterial coating since it fulfils all these criteria. It exhibits low cytotoxicity [2], antibacterial properties [3,4], promotes cell growth [5][6][7][8], resists corrosion [9], can aid antibiotic release [10,11], is simple to produce with control over film thickness [12] and can be attached to a variety of surfaces including silanes [13], metals [9,14], polymers [7,[15][16][17] dentine [18] and even hair [19].…”