Synthesis and characterization of a symmetrically substituted cyclodiphosph(V)azane ligand and its transition metal complexes for antimicrobial and antitumor investigation.

Abstract

A NEW ligand of geminal cyclodiphosph(V)azane derivatives, 1,3-di-[N/-2,6-dimethoxy-4-pyrimidnylsulfanilamide]2,4-di-[N/-2-quinoxalinylsulfanilamide]-2,4dichlorocyclodiphosph(V)azane (H4L 1) was prepared. The ligand and its related complexes were characterized by different physicochemical techniques, namely; IR, UV-vis, mass, 1 H NMR, molar conductance, magnetic, solid reflectance, and thermal analysis. The spectral data revealed that the ligand behaves as ionic in nature and coordinated to the metal ions via enolic-OH of sulphonamide group and pyrimidine-N. The molar conductance data reveal that the complexes were electrolytes, while UV-vis, solid reflectance and magnetic moment data have been shown that the complexes have octahedral geometry. The thermal behavior of the complexes was also studied. The ligand and its metal complexes showed a high to moderate antimicrobial activities against deferent strains of bacteria and fungi, also showed anticancer activity against colon carcinoma HCT116.

Preparation and characterization of novel flame-retardant paint of substituted cyclodiphosph(V)azane sulfonomide and their Cu(II), Cd(II) metal complexes as new additives for exterior wood coating protection

“…Table 2 displays the electronic spectra of the metal complexes in (10 −3 M) DMF at room temperature in the 200–800 nm wavelength range. Complexes show a characteristic absorption band similar to the phosphazo four-member rings assigned of H 2 L ligand, which is shifted to lower wavelengths at 269 nm and 270 nm for [(CuCl 2 ) 2 (H 2 L)(H 2 O) 4 ] and [(CdCl 2 ) 2 (H 2 L)(H 2 O) 4 ] complexes respectively 60 , 61 . For metal complexes, the absorption bands linked to the π–π* transitions are moved to shorter wavelengths at 306 nm and 300 nm.…”

“…This finding confirms that the anions were inside the coordination sphere of the metal complex. 60,61 . For metal complexes, the absorption bands linked to the π-π* transitions are moved to shorter wavelengths at 306 nm and 300 nm.…”