Synthesis and characterization of a novel internal emulsifier derived from sunflower oil for the preparation of waterborne polyurethane and their application in coatings

Shendi, Hasan Kashef; Omrani, Ismail; Ahmadi, Abbas; Farhadian, Abdolreza; Babanejad, Niloofar; Nabid, Mohammad Reza

doi:10.1016/j.porgcoat.2016.11.033

Cited by 69 publications

(16 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The obtained mixture was cooled to room temperature and rinsed with distilled water and sodium bicarbonate solution repeatedly until neutral pH was obtained. ESFO was obtained after drying with MgSO 4 , filtering, evaporation of organic solvent by rotary evaporation, and drying in a vacuum oven overnight [40].…”

Section: Methodsmentioning

confidence: 99%

Sustained delivery of olanzapine from sunflower oil‐based polyol‐urethane nanoparticles synthesised through a cyclic carbonate ring‐opening reaction

Babanejad

Nabid

Farhadian

et al. 2019

IET nanobiotechnol.

Self Cite

View full text Add to dashboard Cite

The forefront horizon of biomedical investigations in recent decades is parcelling-up and delivery of drugs to achieve controlled/targeted release. In this regard, developing green-based delivery systems for a spatiotemporal controlling therapeutic agent have drawn a lot of attention. A facile route based on cyclic carbonate ring-opening reaction has been utilised to synthesise a bio-based polyol-containing urethane bond [polyol-urethane (POU)] as a nanoparticulate drug delivery system of olanzapine in order to enhance its bioavailability. After characterisation, the nanoparticles were also estimated for in vitro release, toxicity, and pharmacokinetic studies. As olanzapine has shown poor bioavailability and permeability in the brain, the sustained release of olanzapine from the designed carriers could enhance pharmacokinetic effectiveness. POU in the aqueous solution formed micelles with a hydrophobic core and embedded olanzapine under the influence of its hydrophobic nature. Drug release from the nanoparticles (90 ± 0.43 nm in diameter) indicated a specific pattern with initial burst release, and then a sustained release behaviour (82 ± 3% after 168 h), by the Higuchi-based release mechanism. Pharmacokinetics assessments of POU-olanzapine nanoparticles were carried in male Wistar rats through intravenous administration. The obtained results paved a way to introduce the POU as an efficient platform to enhance the bioavailability of olanzapine in therapeutic methods.

show abstract

Section: Methodsmentioning

confidence: 99%

Sustained delivery of olanzapine from sunflower oil‐based polyol‐urethane nanoparticles synthesised through a cyclic carbonate ring‐opening reaction

Babanejad

Nabid

Farhadian

et al. 2019

IET nanobiotechnol.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Anti-adhesion materials, patch, drug-delivery carrier, bone-fixing device, suture, tissue-engineered scaffold [40][41][42] Biocompatibility, good mechanical properties, safe, non-toxic [40][41][42] Poor toughness, degradation speed slow, hydrophobicity, lack of reactive side chain groups [40][41][42] Polyurethane Excipients, medical bandage [43][44][45] Low cost, rich resource, good mechanical properties [43,44,46,47] Degradation speed slow [43,46,47] Poly(lactic-glycolic acid) (PLGA)…”

Section: Chitosanmentioning

confidence: 99%

“…Therefore, the development of biodegradable PU materials becomes the key to solving this problem. Currently available biodegradable PU include oligosaccharides-derived PU; lignin, tannin, and bark-derived PU; cellulose derivatives of PU; and starch derivatives of PU [ 44 , 47 ]. Since PU has good biological compatibility and resists thrombosis, biodegradable PU has great development potential in the biomedical field.…”

Section: Polymeric Nanomaterialsmentioning

confidence: 99%

Polymer-Based Nanomaterials and Applications for Vaccines and Drugs

et al. 2018

View full text Add to dashboard Cite

Nanotechnology plays a significant role in drug development. As carriers, polymeric nanoparticles can deliver vaccine antigens, proteins, and drugs to the desired site of action. Polymeric nanoparticles with lower cytotoxicity can protect the delivered antigens or drugs from degradation under unfavorable conditions via a mucosal administration route; further, the uptake of nanoparticles by antigen-presenting cells can increase and induce potent immune responses. Additionally, nanomaterials are widely used in vaccine delivery systems because nanomaterials can make the vaccine antigen long-acting. This review focuses on some biodegradable polymer materials such as natural polymeric nanomaterials, chemically synthesized polymer materials, and biosynthesized polymeric materials, and points out the advantages and the direction of research on degradable polymeric materials. The application and future perspectives of polymeric materials as delivery carriers and vaccine adjuvants in the field of drugs and vaccines are presented. With the increase of knowledge and fundamental understandings of polymer-based nanomaterials, means of integrating some other attractive properties, such as slow release, target delivery, and alternative administration methods and delivery pathways are feasible. Polymer-based nanomaterials have great potential for the development of novel vaccines and drug systems for certain needs, including single-dose and needle-free deliveries of vaccine antigens and drugs in the future.

show abstract

“…The prepared PU-NPs were found to be between 200 and 300 nm in particle size with a polydispersity index ranging from 0.3 to 0.4. Moreover, Shendi, H. K. et al prepared water-borne PU-NPs by using IPDI and modified sun flower oil with the technique of emulsion polymerization [ 48 ]. The film prepared from the waterborne PU-NPs showed excellent thermal and mechanical properties as well as high hardness and tensile strength.…”

Section: Nanosynthesis Of Representative Polymers Used In Construcmentioning

confidence: 99%

Synthesis, Morphologies and Building Applications of Nanostructured Polymers

Shah

2017

Polymers

View full text Add to dashboard Cite

Nanostructured polymers (NSPs) are polymeric materials in the size of nanoscale, normally consisting of nanoparticles, nanofibers, nanowires, nanospheres and other morphologies. Polymer nanoparticles (PNPs) can be fabricated either by physical methods (i.e., solvent evaporation, nanoprecipitation, salting out) or by direct nanosynthesis, using micro-or nanoemulsions with nanoreactor compartments to perform polymerization. Polymer nanofibers (PNFs) can be produced via various techniques and the most commonly used approach is electrospinning, whereby a charged solution of a polymer when exposed to an opposite high electric field is pulled into long thin nanofibers. NSPs in general exhibit enhanced properties such as excellent structural and mechanical properties, making them promising candidates for some particular building applications. A variety of PNFs have been developed and used for noise and air pollution filtration. Moreover, PNFs can also be fabricated with phase change materials which are usually employed for thermal energy storage in construction industry. In this review, we will summarize the morphologies and nanosynthesis methods of NSPs, in particular, PNPs and PNFs. In addition, representative NSPs mainly used in construction are introduced for building applications.

show abstract

Synthesis and characterization of a novel internal emulsifier derived from sunflower oil for the preparation of waterborne polyurethane and their application in coatings

Cited by 69 publications

References 32 publications

Sustained delivery of olanzapine from sunflower oil‐based polyol‐urethane nanoparticles synthesised through a cyclic carbonate ring‐opening reaction

Sustained delivery of olanzapine from sunflower oil‐based polyol‐urethane nanoparticles synthesised through a cyclic carbonate ring‐opening reaction

Polymer-Based Nanomaterials and Applications for Vaccines and Drugs

Synthesis, Morphologies and Building Applications of Nanostructured Polymers

Contact Info

Product

Resources

About