Synthesis and Characterization of 2-imino-3–(2-Hydroxylphenyl)-1- Thiazolidin-4-one Substituted Ammine Complexes of Cr(III), Co(III), Ni(II) and Cu(II)

Abstract

Many metal complexes of biologically important ligands are more effective than their free ligands 1. Mixed ligand complexes have a pivotal role in biological chemistry 2 as these create specific structures 3 and have been implicated in the storage and transport of active substances through membranes. Among these ligands are thiazolidnones, derivatives of thiazolidine. Plenty of thiazolidnone derivatives have been found to exhibit profound broad spectrum of biological properties, viz. bactericidal 4-5 , fungicidal 6 , anticonvalsant 7 , anti-inflammatory 8 , antitumor 9 , anti-HIV 10 etc. Although reports on synthesis, characterization and biological properties of mixed ligand complexes derived either by direct