Synthesis and characterization for novel Cu(II)-thiazole complexes-dyes and their usage in dyeing cotton to be special bandage for cancerous wounds

El‐Metwaly, Nashwa M.; Althagafi, Ismail; Khedr, Abdalla M.; Al‐Fahemi, Jabir H.; Katouah, Hanadi A.; Hossan, Aisha; Al-dawood, Aisha Y.; Al‐Hazmi, Gamil A.A.

doi:10.1016/j.molstruc.2019.05.080

Cited by 22 publications

(22 citation statements)

References 35 publications

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“… 11 , 20 , 30 In recent years, antioxidant activity and possible antibacterial activity of metal complexes with quinoline derivatives have been reported. 11 , 14 , 20 , 21 , 30 , 31 …”

Section: Introductionmentioning

confidence: 99%

“…The efficiencies of metal complexes having biological activities depend on the nature of both metal ions and the ligands that the complexes are made from. Accordingly, metal complexes synthesized from single ligands with different metal ions exhibited different biological properties. ,, In recent years, antioxidant activity and possible antibacterial activity of metal complexes with quinoline derivatives have been reported. ,,,,, …”

Section: Introductionmentioning

confidence: 99%

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Novel Zinc(II) and Copper(II) Complexes of 2-((2-Hydroxyethyl)amino)quinoline-3-carbaldehyde for Antibacterial and Antioxidant Activities: A Combined Experimental, DFT, and Docking Studies

Damena

Alem

Zeleke³

et al. 2022

ACS Omega

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In the present work, two novel complexes of zinc(II) and copper(II) were synthesized from the ligand 2-((2-hydroxyethyl)amino)quinoline-3-carbaldehyde ( H 2 L ) in a 1:2 metal-to-ligand ratio in methanol. The complexes were characterized by UV–visible spectroscopy, fluorescence spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, powder X-ray diffraction (XRD), scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDX), mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, and thermogravimetric analysis (TGA) experimental techniques and density functional theory (DFT) calculations. The spectral data revealed that the mono-deprotonated ( HL ) ligand acted as a bidentate ligand, which bound to both Zn(II) and Cu(II) ions via the nitrogen atom of the amine (N–H) and the hydroxyl (O–H) groups through the deprotonated oxygen atom. Formation constants and thermal analysis indicated that both metal complexes are stable up to 100 °C with thermodynamically favored chemical reactions. The Cu(II) complex showed antibacterial activities with the zones of inhibition of 20.90 ± 2.00 mm against Pseudomonas aeruginosa , 19.69 ± 0.71 mm against Staphylococcus aureus , and 18.58 ± 1.04 mm against Streptococcus pyogenes . These results are relatively higher compared with the Zn(II) complex at the same concentration. The minimum inhibitory concentration (MIC) results for the complexes also showed similar trends against the three bacteria. On the other hand, radical scavenging activities of both Cu(II) and Zn(II) complexes showed half-maximal inhibitory concentrations (IC 50 ) of 4.72 and 8.2 μg/mL, respectively, while ascorbic acid (a positive control) has a value of 4.28 μg/mL. The Cu(II) complex exhibited better communication with the positive control, indicating its potential use for biological activities. The calculated and in silico molecular docking results also strongly support the experimental results.

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“… 11 , 20 , 30 In recent years, antioxidant activity and possible antibacterial activity of metal complexes with quinoline derivatives have been reported. 11 , 14 , 20 , 21 , 30 , 31 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Novel Zinc(II) and Copper(II) Complexes of 2-((2-Hydroxyethyl)amino)quinoline-3-carbaldehyde for Antibacterial and Antioxidant Activities: A Combined Experimental, DFT, and Docking Studies

Damena

Alem

Zeleke³

et al. 2022

ACS Omega

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“…The first stage was addition of hydrogen atoms over selected receptors and then fixed the potential energy. Secondly, the site finder was applied over alpha‐site in protein‐helix, which followed by choosing the domain type . Finally, the two docking sides (inhibitor & protein) are ready for starting the process, which leave for long time to execute the complexation process.…”

Section: Methodsmentioning

confidence: 99%

Green synthesis approach for Fe (III), Cu (II), Zn (II) and Ni (II)‐Schiff base complexes, spectral, conformational, MOE‐docking and biological studies

Al‐Hazmi

Abou‐Melha

El‐Metwaly

et al. 2019

Applied Organom Chemis

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Green synthesis of Fe (III), Cu (II), Zn (II) and Ni (II)‐Schiff's‐base complexes from 2‐oxo‐N‐(pyridine‐2‐yl)‐2‐(2‐(1‐(pyridin‐2‐yl)ethylidene)hydrazinyl)acetamide(H2L)ligand. All new complexes were characterized via several spectroscopic and analytical techniques, to establish their molecular and structural formulae. All complexes appeared have 1:1 molar ratio (M:L). The ligand contributed as a neutral poly‐dentate towards the metal ions. Moreover, material‐studio program was used to predict the most fitted atomic‐skeletons for investigated compounds by applying DFT method. MOE docking module (vs. 2015) was used to examine the degree of inhibition for new compounds versus three infected‐cell proteins (1bqb, 2gt1 and 4esw). Also, antimicrobial and colorimetric assess for compounds that bind DNA were performed

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“…They have become one of the most extensively utilized textiles for various applications such as apparel, personal care, and medical products, automotives, oil-spill cleaning, as well as heat and sound insulation. 40,41 However, the inherent flammability, low waterproofing, and microbial infection of cotton substrates have limited the scope of their applications. [42] The objective of the current work was to impart superhydrophobic, photoluminescence, and flame-retardant properties to cotton fibres due to the significance of producing multiple functional cellulosic products for both apparel and highperformance purposes.…”

Section: Introductionmentioning

confidence: 99%

Preparation of multifunctional long‐persistent photoluminescence cellulose fibres

et al. 2021

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Synthesis and characterization for novel Cu(II)-thiazole complexes-dyes and their usage in dyeing cotton to be special bandage for cancerous wounds

Cited by 22 publications

References 35 publications

Novel Zinc(II) and Copper(II) Complexes of 2-((2-Hydroxyethyl)amino)quinoline-3-carbaldehyde for Antibacterial and Antioxidant Activities: A Combined Experimental, DFT, and Docking Studies

Novel Zinc(II) and Copper(II) Complexes of 2-((2-Hydroxyethyl)amino)quinoline-3-carbaldehyde for Antibacterial and Antioxidant Activities: A Combined Experimental, DFT, and Docking Studies

Green synthesis approach for Fe (III), Cu (II), Zn (II) and Ni (II)‐Schiff base complexes, spectral, conformational, MOE‐docking and biological studies

Preparation of multifunctional long‐persistent photoluminescence cellulose fibres

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