Synthesis and characterisation of novel composite sunscreens containing both avobenzone and octocrylene motifs

Abstract

Compounds 10a–10e and 14a/b contain elements of the two established sunscreen molecules avobenzone and octocrylene. The compounds were prepared, characterised and were found to have broad-wavelength, UV-absorbing properties.

Characteristic Photoprotective Molecules from the Sphagnum World: A Solution-Phase Ultrafast Study of Sphagnic Acid

“…Based on SphA’s absorption profile and photodynamics, we suggest the molecule for use as support to sunscreen formulations containing avobenzone, to combat the generation of deleterious free radicals demonstrated as arising from avobenzone’s exposure to UV-B, as well as providing photoprotection in the UV-B region. As the toxicology of commercial UV filters continues to be unravelled, it is possible that natural alternatives, such as SphA, may supplant other existing sunscreen ingredients (e.g., octocrylene, currently used in formulations containing avobenzone) [ 51 , 52 , 53 ]. Future work such as ab initio computational studies may provide an understanding of the fast relaxation rates exhibited by SphA.…”