Synthesis and biological research of new imidazolone-sulphonamide-pyrimidine hybrids as potential EGFR-TK inhibitors and apoptosis-inducing agents

Binjawhar, Dalal Nasser; Katouah, Hanadi A.; Alshaye, Najla A.; Alharthi, Jawaher; Alsharif, Ghadi; Elsaid, Fahmy G.; Fayad, Eman; Abu Almaaty, Ali H.

doi:10.1039/d4ra03157a

RSC Adv.

2024

DOI: 10.1039/d4ra03157a

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Synthesis and biological research of new imidazolone-sulphonamide-pyrimidine hybrids as potential EGFR-TK inhibitors and apoptosis-inducing agents

Dalal Nasser Binjawhar,

Hanadi A. Katouah,

Najla A. Alshaye

et al.

Abstract: A sequence of novel imidazolone-sulphonamide-pyrimidine hybrids was synthesized and evaluated for in vitro cytotoxicity against MCF-7 breast cancer cell line.

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Synthesis and biological research of new imidazolone-sulphonamide-pyrimidine hybrids as potential EGFR-TK inhibitors and apoptosis-inducing agents

Abstract: A sequence of novel imidazolone-sulphonamide-pyrimidine hybrids was synthesized and evaluated for in vitro cytotoxicity against MCF-7 breast cancer cell line.

Cited by 0 publications

References 43 publications

No citations

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