Synthesis and biological properties of methyl-substituted imidazo[2,1-b]benzothiazoles

Красовский, А. Н.; Grin, N. P.; Soroka, I. I.; Кочергин, П. М.; Bogamyreva, E. I.

doi:10.1007/bf00778013

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“…In addition, pyrazolines have played a crucial part in heterocyclic chemistry and also used broadly in organic synthesis [16][17][18][19][20] . Benzothiazole and its derivatives [21][22][23][24][25] have been known as a class of medicinal importance. Benzothiazole derivatives represent an extensive group of heterocyclic compounds, several of which have already found application in the medical sphere as medicines 26 as well as in agriculture 27 .…”

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confidence: 99%

Synthesis and Characterization of Some Benzothiazolopyrazoline Derivatives

Pareek

Paliwal

Jain

2020

Int. J. Eng. Tech. Mgmt. Res.

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A new route for the synthesis of benzothiazolopyrazoline derivatives has been developed using various chalcone derivatives and 2-hydrazinobenzothiazole and piperidine catalyst. The product obtained in shorter reaction times and piperidine behaves as good catalyst for the cycloaddition rof chalcone and 2-hydrazinobenzothiazole. The reaction carried out in aqueous-ethanol medium at reflux condition and product obtained in high yield.

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