“…Moreover, 1,3,5-triazine based molecules have been found to exhibit multiple bioactivities such as adenosin receptor antagonists, protein kinases, HIV-1 reverse transcriptase, urate oxidase, estrogen receptor beta, mTOR inhibitors, and so on . In particular, α-(1,3,5-triazinylthio)-ketones have been reported to display various activities, including antitumor activity, antimalarial activity, antibacterial activity, antileishmanial activity, antiviral activity, and for treating neurological disorders. − For this reason, the development of efficient protocols for α-(1,3,5-triazinylthio)-ketones has always been an active area of research in both synthetic and medicinal chemistry. In recent years, several examples of the C–C bond cleavage and C–C or C–heteroatom bond reconstruction of 1,3-dicarbonyl compounds have been reported .…”