Synthesis and biological evaluation of 4-dimethylaminobenzaldehyde derivatives of Schiff bases metal complexes: A review

Ali, Aemin; Pervaiz, Muhammad; Saeed, Zohaib; Younas, Umer; Bashir, Rashida; Samiullah, -; Bukhari, Syed Majid; Ali, Faisal S.; Jelani, Seemal; Rashid, Ayoub; Adnan, Ahmad

doi:10.1016/j.inoche.2022.109903

Cited by 10 publications

(1 citation statement)

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“…Five unpaired electrons are represented by the measured magnetic moment of the Mn(II) complex, which is 5.44 B.M., indicating a high spin octahedral environment. [37] The d shell is full and not available for bonding in Cd(II) and Zn(II) complexes. Due to the d electrons' absence from metallic bonding, the metal is relatively soft when combined with other transition metals.…”

Section: Electronic Spectra and Magnetic Moment Measurementsmentioning

confidence: 99%

N′-((E)-3,3-Diphenyl-2,3-Dihydro-1H-Inden-1-Ylidene)-2-((Z)-2-Oxoindolin-3-Ylidene)Hydrazine-1-Carbothiohydrazide Ligand and Its Complexes: Spectroscopic, Molecular Orbital, Molecular Docking, Structural Study and Antimicrobial Activity

Zayed,

El-Sayed,

Albalawi

et al. 2023

Preprint

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New Schiff base ofN'-((E)-3,3-diphenyl-2,3-dihydro-1H-inden-1-ylidene)-2-((Z)-2-oxoindolin-3-ylidene)hydrazine-1-carbothiohydrazide (HL) and its Co(II),Ni(II), Fe(III), Cu(II), Cd(II), Zn(II) and Mn(II) complexes were created, isolated, and characterized by analytical analysis in good yields of 60 to 90%, UV–Vis, magnetic measurements, molar conductivity, and FT-IR. Additionally, mass spectrometry was used to examine the new ligand complexes' structural characteristics.1H NMR spectroscopy and elemental analysis. Depending on the electronic spectra and magnetic susceptibility measurements, these complexes are predicted to have octahedral molecular geometry. As an example, the quantum chemical properties, bond lengths, and bond angles were discussed. The structural formula for the examined ligand was improved using the Gaussian09 tool. The DFT/B3LYP method was used to calculate the energy gaps and other crucial theoretical features. The prepared hydrazine ligand complexes Co (II), Ni (II), Fe (III), Cu (II), Cd (II), Zn (II) and Mn (II) complexes were evaluated for its antimicrobial properties. As antimicrobial agents, it was found that the organic ligand was less biologically active than the targeted complexes. Gram positive bacteria (3ty7-Staphylococcus), Gram negative bacteria (3t88-Escherichia coli), and fungi (5k04-Candida albicans) all have crystal structures that interact well with the chemicals in the title, according to molecular docking.

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Section: Electronic Spectra and Magnetic Moment Measurementsmentioning

confidence: 99%