Synthesis and biological evaluation of levofloxacin core-based derivatives with potent antibacterial activity against resistant Gram-positive pathogens

Synthesis and Insecticidal Activity of New Quinoline Derivatives Containing Perfluoropropanyl Moiety

“…For instance, the famous anti-malaria drug quinine is exacted from the congeneric plants firstly. Neither natural quinoline derivatives nor synthetic quinoline derivatives always displayed diversity activities, such as antioxidant activity [1], antitubercular agents [2], trypanocidal activities [3], anticancer [4], antibacterial activity [5], aromatase inhibitors [6], and multi-trypanosomatid activity [7]. So the synthesis of novel quinoline derivatives has been attracted by many organic chemists.…”

Synthesis and in vivo fungicidal activity of some new quinoline derivatives against rice blast

“…In modern synthetic chemistry, quinoline compounds have been applied in many fields, such as coordination chemistry, organometallic chemistry, asymmetric synthesis, medicinal chemistry, pesticide chemistry, and materials chemistry. Quinoline is one of the most common chemical skeletons of synthesis chemistry and has been used to discover a number of important bioactive compounds, such as anti‐tubercular agents, anti‐cancer drugs, antioxidants, aromatase inhibitors, multi‐trypanosomatids, trypanocidals, antibacterial agents, etc. Therefore, the synthesis of new quinolone derivatives has attracted many organic chemists.…”

Continuous Hydrogenolysis of N-Diphenylmethyl Groups in a Micropacked-Bed Reactor

“…In this paper, a flow system based on μPBRs was developed to perform the H 2 -based hydrogenolysis. The hydrogenolysis of N -diphenylmethylazetidin-3-ol (DMAOL) to 3-azetidinol (Figure ) was employed as the model reaction, which is an organic pharmaceutical intermediate for the synthesis of antibiotics and antibacterial agents . The catalysts and solvents suitable for this kind of reaction were first screened and then the reaction performance and kinetics were investigated.…”