Synthesis and Biological Activity of New Derivatives of Thiazolidine and Oxazepine-Linked to Pyridine Moieties

Abstract

This research includes reaction and condensation between substituted 4-aminopyridine and 4-(N, N-dimethyl amino benzaldehyde) to produce Schiff base derivative (3), the compound (3) was selected to react with a different compound such as Thioglycolic acid, Phthalic anhydride, and maleic anhydride, to produced new ring of Thiazolidine derivatives and oxazepine derivatives structures (4,5,6,7,8,9,10,11,12), respectively. The final compound was characterized the structure by Fourier transform-infrared spectroscopy, H-Nuclear magnetic resonance (H-NMR) in addition to the Carbon, Hydrogen, Nitrogen (CHN) analyzer. Biological activity has been considered for the final structures and achievements of multi drugs.

Synthesis, Characterization, and Biological Activity of a Novel SA-g-p(AAc-co-AM)/ZnO NP Hydrogel Composite

“…This study focuses on two primary bacterial classifications: Gram-positive and Gram-negative bacteria [4,5]. Escherichia coli, a Gram-negative and facultatively anaerobic bacterium, is commonly found in the intestines of animals and humans and extends its presence to certain foods and plants [6,7].…”