2006
DOI: 10.1016/j.bmc.2006.07.015
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Synthesis and biological activity of Schiff and Mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety

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Cited by 488 publications
(274 citation statements)
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“…Many reports have demonstrated that aromatic nucleus Schiff bases had good bioactivities (Karthikeyan et al, 2006). It is also reported that salicylaldehyde derivatives, with one or more haloatoms in the aromatic ring, showed a variety of biological activities (Li, Guo, & Jiang, 2010).…”
Section: Introductionmentioning
confidence: 99%
“…Many reports have demonstrated that aromatic nucleus Schiff bases had good bioactivities (Karthikeyan et al, 2006). It is also reported that salicylaldehyde derivatives, with one or more haloatoms in the aromatic ring, showed a variety of biological activities (Li, Guo, & Jiang, 2010).…”
Section: Introductionmentioning
confidence: 99%
“…Schiff bases are a class of compound which is known to exhibit antifungal activity [26,27]. Schiff bases derived from 5-nitrosalicylaldehyde and amines, such o-and p-aminophenols, were prepared by Murthy et al [28] and a number of metal complexes of the resulting ligands were tested for their antibacterial activity.…”
Section: Introductionmentioning
confidence: 99%
“…Infrared spectra (KBr, 4000-400 cm -1 ) have been recorded on SHIMADZU Fourier transform spectrophotometer. The NMR spectra were recorded in Bruker AMX 500 NMR spectrometer operating at 5400 MHz has been utilized for recording 1 H NMR spectra and 100 MHz for 13 C spectra in CDCl 3 solvent using TMS as internal standard. Ultra-sonication was done at 3.5L 100 at Govt.…”
Section: Methodsmentioning
confidence: 99%
“…Schiff bases form a significant class of compounds in medicinal and pharmaceutical chemistry with several biological applications which includes antibacterial [1][2][3] , antifungal 4 and antitumor activities 5 . Conventionally, Schiff's bases can be prepared by refluxing the primary amines and aldehyde/ketone in an organic solvents and presence of traces of acid or base.…”
Section: Introductionmentioning
confidence: 99%