Synthesis and bioevaluation of novel stilbene-based derivatives as tubulin/HDAC dual-target inhibitors with potent antitumor activities in vitro and in vivo

Exploring the antitumor potential of novel quinoline derivatives via tubulin polymerization inhibition in breast cancer; design, synthesis and molecular docking

“…This is in alignment with several studies that showed the ability of different quinoline derivatives to inhibit tubulin polymerization. 28,47,48 2.2.6. Tubulin expression assay.…”