Synthesis and binding character of ether-ester-ethyleneurea podands and macrocycles-synthetic nactin analogs

CsF-Si(OEt)4 catalyzed addition of (hetero)aromatic amides to ethyl acrylate

“…The addition of amines to a,b-unsaturated ketones and esters catalyzed by FeCl 3 , 3 InCl 3 , 4 lanthanide iodides, 5 and copper 6 has been reported. The Nconjugate additions of a thiolactam and of a urea to methyl acrylate have been studied 7 , 8 using NaOH in THF and K 2 CO 3 -BnEt 3 N Cl À -DMF catalytic systems, respectively. The CsF-Si(OEt) 4 system was proposed by Corriu and coworkers [9][10][11][12] as promoting Michael type reactions.…”