Synthesis and application of core‐shell complex‐imprinted polymer for the solid‐phase extraction of melamine from dairy products

Abstract

A core-shell complex-imprinted polymer (CIP) was synthesized and evaluated for selective extraction of melamine from dairy products. The CIP synthesis based on surface modification of home-made silicon microspheres was conducted via a metal complex as functional monomer, ethylene glycol dimethylacrylate as cross-link and melamine as template. The resulting CIP was characterized by SEM and Fourier transform infrared spectroscopy. When the amount of silica microspheres was 100 mg and the molar ratio of copper(II) methacrylate to EDGMA was 1:10, well-dispersed particles were obtained. The complex-imprinted SPE condition was optimized and the maximum enrichment factor of melamine can be up to 40. The reliability of complex-imprinted SPE for extraction and enrichment of melamine was investigated and proved by using spiked samples including milk and milk powder with the recoveries ranging from 87 to 92%.

Magnetic molecularly imprinted polydopamine nanolayer on multiwalled carbon nanotubes surface for protein capture

“…The adsorption capacity (Q) of the MWNTs@Fe 3 O 4 @MIPs for template protein was calculated by the following equation [23]:…”

Application of a magnetic molecularly imprinted polymer for the selective extraction and trace detection of lamotrigine in urine and plasma samples

“…Molecularly imprinted polymers (MIPs) are artificial polymers, which are formed in the presence of a target molecule that finally is removed by the proper solvents; therefore, the obtained specific cavities are complementary to the target molecule in shape, size, and functional groups. The use of MIPs has been developed in various fields such as extraction , sensors , catalysis , and drug delivery . In recent years, the combination of MIPs and other sample‐preparation techniques such as SPE, solid‐phase microextraction, and matrix solid‐phase dispersion has opened a new window for the selective extraction and recognition of target molecules from complex matrices .…”

Rapid and selective screening of melamine in bovine milk using molecularly imprinted matrix solid-phase dispersion coupled with liquid chromatography-ultraviolet detection

“…Owing to its high nitrogen content and low price, MEL was intentionally added to raw milk to increase its total nitrogen concentration, which will possibly result in higher measurement of protein [2]. Though, low level MEL does not pose danger to humans, high and prolonged dietary exposure to MEL can increase the incidence of urinary bladder tumors and result in the formation of lethal kidney stones [3,4], especially when combined with cyanuric acid [5].…”